AN ULTRA-HIGH PERFORMANCE LIQUID CHROMATOGRAPHY WITH TANDEM MASS SPECTROMETRY METHOD FOR DETERMINATION OF 10 ALKALOIDS IN BEAGLE DOG PLASMA AFTER THE ORAL ADMINISTRATION OF THE CORYDALIS YANHUSUO W.T. WANG EXTRACT AND YUANHUZHITONG TABLETS

An Ultra-High Performance Liquid Chromatography with Tandem Mass Spectrometry Method for Determination of 10 Alkaloids in Beagle Dog Plasma after the Oral Administration of the Corydalis yanhusuo W.T. Wang Extract and Yuanhuzhitong Tablets

This study has developed a sensitive and simple ultra-high performance liquid chromatography-electrospray ionization-tandem mass spectrometry method for the simultaneous determination of corydaline, dehydrocorydaline, tetrahydropalmatine, protopine, palmatine, tetrahydroberberine, columbamine, berberine, coptisine and berberrubine in beagle dog pla

read more



Data driven model discovery and interpretation for CAR T-cell killing using sparse identification and latent variables

In the development of cell-based cancer therapies, quantitative mathematical models of cellular interactions are instrumental in understanding treatment efficacy.Efforts to validate and interpret mathematical models of cancer cell growth and death hinge first on proposing a precise mathematical model, then analyzing experimental data in the context

read more